Search results for " working memory"

showing 10 items of 55 documents

Dysregulation of C-X-C motif ligand 10 during aging and association with cognitive performance

2017

International audience; Chronic low-grade inflammation during aging (inflammaging) is associated with cognitive decline and neurodegeneration; however, the mechanisms underlying inflammaging are unclear. We studied a population (n = 361) of healthy young and old adults from the MyoAge cohort. Peripheral levels of C-X-C motif chemokine ligand 10 (CXCL10) was found to be higher in older adults, compared with young, and negatively associated with working memory performance. This coincided with an age-related reduction in blood DNA methylation at specific CpGs within the CXCL10 gene promoter. In vitro analysis supported the role of DNA methylation in regulating CXCL10 transcription. A polymorph…

0301 basic medicinegamma interferon inducible protein 10genomic DNAAlzheimerin tautiEpigenesis GeneticCohort StudiesCXCL10 geneCognitionsingle nucleotide polymorphismcognitive defectCognitive declineAged 80 and overCerebral Cortexeducation.field_of_studyprefrontal cortexDNA methylationGeneral NeuroscienceadultNeurodegenerationneurodegenerationta3141U937 CellsMethylationta3142Alzheimer's diseasecohort analysisDNA-metylaatioagedfemalepriority journalepigenetiikkaDNA methylationAlzheimer's diseaseAlzheimer diseasetranscription regulationAlzheimer’s diseasekognitiiviset taidotmedicine.medical_specialty[SDV.MHEP.AHA] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]in vitro studyAdolescentheredityPopulationBiologyArticleworking memoryYoung Adult03 medical and health sciencesCognitive agingpromoter regionmaleMemoryInternal medicineJournal Articlemedicine[SDV.MHEP.AHA]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]HumansCXCL10controlled studyEpigeneticshumanbrain levelNeurodegenerationeducationepigeneticscognitive aginghuman cellagingdisease associationmedicine.diseasemajor clinical studyInflammagingChemokine CXCL10gamma interferon inducible protein 10; genomic DNA adult; age; aged; aging; Alzheimer disease; Article; brain level; cognitive defect; cohort analysis; controlled study; CpG island; CXCL10 gene; disease association; DNA methylation; epigenetics; female; heredity; human; human cell; in vitro study; inflammation; major clinical study; male; prefrontal cortex; priority journal; promoter region; single nucleotide polymorphism; transcription regulation; working memory; Alzheimer's disease; Cognitive aging; DNA methylation; Epigenetics; Inflammaging; Neurodegeneration030104 developmental biologyEndocrinologyikääntyminenageinflammationNerve DegenerationCpG islandinflammagingNeurology (clinical)Geriatrics and GerontologyHeLa CellsDevelopmental BiologyNeurobiology of Aging
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Executive functions in kindergarten children at risk for developmental coordination disorder

2018

Executive functioning (EF) is a key cognitive process for development. Little is known about EF in Kindergarten children at risk for developmental coordination disorder (DCD), despite this age being one of the most critical and intensive period of motor and cognitive development. In our investigation we compared EF in kindergarten children at risk for DCD with Typically Developing (TD) children. Participants were 36 Italian children, 18 at risk for DCD (9 boys and 9 girls) who had a mean age of 4.6 years and 18 TD (9 boys and 9 girls) who had a mean age of 4.6. Executive functions were measured by tasks targeting cold executive functioning (working memory, fluency, inhibitory control) and t…

3304media_common.quotation_subjecteducationShort-term memoryDevelopmental Coordination Disorder; executive functioning; fluency; inhibitory Control; kindergarten; working memory; 3304; Health Professions (miscellaneous); Developmental and Educational PsychologyDevelopmental Coordination DisorderHealth Professions (miscellaneous)working memoryEducationDevelopmental psychologySettore M-PSI/04 - Psicologia Dello Sviluppo E Psicologia Dell'EducazioneDevelopmental and Educational Psychologykindergarten0501 psychology and cognitive sciencesfluencyAt-risk studentsmedia_commonPsychomotor learningWorking memory05 social sciences050301 educationCognitionSelf-controlinhibitory ControlExecutive functionsChild developmentPsychologyexecutive functioning0503 education050104 developmental & child psychologyEuropean Journal of Special Needs Education
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Working memory capacity affects trade-off between quality and quantity only when stimulus exposure duration is sufficient : Evidence for the two-phas…

2019

AbstractThe relation between visual working memory (VWM) capacity and attention has attracted much interest. In this study, we investigated the correlation between the participants’ VWM capacity and their ability to voluntarily trade off the precision and number of items remembered. The two-phase resource allocation model proposed by Ye et al. (2017) suggests that for a given set size, it takes a certain amount of consolidation time for an individual to control attention to adjust the VWM resources to trade off the precision and number. To verify whether trade-off ability varies across VWM capacity, we measured each individual’s VWM capacity and then conducted a colour recall task to examin…

AdultMale0301 basic medicinelcsh:MedicineStimulus (physiology)Positive correlationTrade-offArticleCorrelationvisual working memory03 medical and health sciences0302 clinical medicineHuman behaviourPhase modelHumansAttentionlcsh:ScienceMathematicsMultidisciplinaryRecallWorking memorylcsh:RWorking memorylaatukapasiteettityömuistiStimulus exposureMemory Short-Term030104 developmental biologyMental RecallVisual Perceptionlcsh:QFemale030217 neurology & neurosurgeryCognitive psychology
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Two systems of maintenance in verbal working memory: evidence from the word length effect.

2013

The extended time-based resource-sharing (TBRS) model suggested a working memory architecture in which an executive loop and a phonological loop could both support the maintenance of verbal information. The consequence of such a framework is that phonological effects known to impact the maintenance of verbal information, like the word length effect (WLE), should depend on the use of the phonological loop, but should disappear under the maintenance by the executive loop. In two previous studies, introducing concurrent articulation in complex span tasks barely affected WLE, contradicting the prediction from the TBRS model. The present study re-evaluated the WLE in a complex span task while co…

AdultMaleAdolescentCognitive NeuroscienceMnemonicsShort-term memorylcsh:MedicineSocial and Behavioral SciencesVerbal learningTask (project management)Young AdultMemoryHuman PerformancePsychologyHumansWorking Memorylcsh:ScienceBiologyBehaviorMultidisciplinaryRecallVerbal BehaviorWorking memorylcsh:RCognitive PsychologyExperimental PsychologyLinguisticsPhonologyVerbal LearningMental HealthMemory Short-TermMental RecallMedicineFemalelcsh:QBaddeley's model of working memoryAttention (Behavior)PsychologyArticulation (phonetics)Research ArticleNeuroscienceCognitive psychologyPLoS ONE
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Strategic inhibition of distractors with visual working memory contents after involuntary attention capture

2017

AbstractPrevious research has suggested that visual working memory (VWM) contents had a guiding effect on selective attention, and once participants realized that the distractors shared the same information with VWM contents in the search task, they would strategically inhibit the potential distractors with VWM contents. However, previous behavioral studies could not reveal the way how distractors with VWM contents are inhibited strategically. By employing the eye-tracking technique and a dual-task paradigm, we manipulated the probability of memory items occurring as distractors to explore this issue. Consistent with previous behavioral studies, the results showed that the inhibitory effect…

AdultMaleAdolescentEye MovementsInvoluntary attentionhuman cognitionlcsh:MedicineArticle050105 experimental psychologyTask (project management)visual working memorysilmänliikkeetYoung Adult03 medical and health sciences0302 clinical medicineBehavioral studyHumansAttention0501 psychology and cognitive sciencesSelective attentionlcsh:ScienceInhibitory effectVisual searchAnalysis of VarianceMultidisciplinaryWorking memorylcsh:R05 social sciencestyömuistikognitiotiedeMemory Short-TermVisual Perceptionlcsh:QFemalePsychology030217 neurology & neurosurgeryeye-tracking techiquesCognitive psychologyScientific Reports
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Influence of articulation rate on two memory tasks in young and older adults.

2008

This study investigated the relation between phonological loop functioning and age. Phonological loop is a time-based subsystem of the Working Memory Model of Baddeley and Wilson, which uses rehearsal of information as an active process to avoid phonological decay. Performance differences were examined between young and older adults in two speech-based memory tasks, such as the immediate serial recall of words and the Digit Ordering Task. Analysis showed that performance on both tasks was lower for the older group. Articulation rate was also measured to test the hypothesis that the impairment of some cognitive functions in adults can be associated to their slowness or the greater time need…

AdultMaleRecallProcess (engineering)Age FactorsExperimental and Cognitive PsychologyCognitionMiddle AgedSensory SystemsNumerical digitTask (computing)Speech Production MeasurementMemoryMental RecallHumansSpeechFemaleBaddeley's model of working memoryArticulation (phonetics)SlownessPsychologyCognitive psychologyPerceptual and motor skills
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Working memory and everyday cognition in adults with Down's syndrome.

2001

A number of previous studies have suggested that young people with Down's syndrome (DS) have a specific deficit of the phonological loop component of the working memory. However, there have also been studies which have proposed a specific deficit of the central executive component of working memory and suggested similarities of working memory functioning with patients with Alzheimer's disease. Fifteen middle-aged people with DS were matched for their individual scores of non-verbal intelligence to 15 individuals with mixed aetiology of intellectual disability. A versatile range of tasks was used in order to evaluate the functioning of working memory components. In addition, several everyday…

AdultMalemedia_common.quotation_subjectNeuropsychological TestsSerial LearningAffect (psychology)Developmental psychologyArts and Humanities (miscellaneous)Visual memoryAlzheimer DiseasePhoneticsPerceptionIntellectual disabilityActivities of Daily LivingmedicineHumansAttentionmedia_commonWorking memoryRehabilitationRetention PsychologyCognitionMiddle AgedVerbal Learningmedicine.diseasePsychiatry and Mental healthNeurologyPattern Recognition VisualMental RecallFemaleNeurology (clinical)Baddeley's model of working memoryChildhood memoryDown SyndromePsychologyPsychomotor PerformanceJournal of intellectual disability research : JIDR
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Don't stop me now: Hampered retrieval of action plans following interruptions

2020

How can we retrieve action plans in working memory (WM) after being distracted or interrupted? The present EEG study investigated this question using a WM task in which a random sequence of single numbers (1-4 and 6-9) was presented. In a given trial, participants had to decide whether the number presented in the preceding trial was odd or even. Additionally, interfering stimuli were randomly presented in 25% of all trials, requiring the participants to either ignore a colored number (distraction) or respond to it (interruption) while maintaining the previously formed action plan in WM. Our results revealed a detrimental impact of interruptions on WM performance in trials after interrupting…

AdultMalemedicine.medical_specialtyAdolescentCognitive NeuroscienceExperimental and Cognitive PsychologyElectroencephalographyStimulus (physiology)AudiologyMotor Activity050105 experimental psychology03 medical and health sciencesExecutive FunctionYoung Adult0302 clinical medicineDevelopmental NeuroscienceDistractionP3bmedicineHumans0501 psychology and cognitive sciencesBiological Psychiatrymedicine.diagnostic_testEndocrine and Autonomic SystemsWorking memoryGeneral Neuroscience05 social sciencesBrain WavesEvent-Related Potentials P300Neuropsychology and Physiological PsychologyMemory Short-TermNeurologyMental RecallFemaleinterruptions ; distractions ; P3b ; mu/beta suppression ; EEG ; working memoryPsychology030217 neurology & neurosurgeryPsychomotor Performance
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Music lessons improve auditory perceptual and cognitive performance in deaf children

2014

Despite advanced technologies in auditory rehabilitation of profound deafness, deaf children often exhibit delayed cognitive and linguistic development and auditory training remains a crucial element of their education. In the present cross-sectional study, we assess whether music would be a relevant tool for deaf children rehabilitation. In normal-hearing children, music lessons have been shown to improve cognitive and linguistic-related abilities, such as phonetic discrimination and reading. We compared auditory perception, auditory cognition, and phonetic discrimination between 14 profoundly deaf children who completed weekly music lessons for a period of 1.5 to 4 years and 14 deaf child…

Auditory perceptionAuditory scene analysisauditory working memorymedia_common.quotation_subjectbehavioral disciplines and activitieslcsh:RC321-571Behavioral NeurosciencePerceptionReading (process)phonetic discriminationotorhinolaryngologic diseasesEffects of sleep deprivation on cognitive performancelcsh:Neurosciences. Biological psychiatry. NeuropsychiatryBiological PsychiatryOriginal Researchmedia_commonWorking memoryCongenitally deaf childrenCognitionPsychiatry and Mental healthNeuropsychology and Physiological PsychologyNeurologyAuditory PerceptionPsychologymusic trainingPeriod (music)NeuroscienceCognitive psychologyFrontiers in Human Neuroscience
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A cognitive architecture for inner speech

2020

Abstract A cognitive architecture for inner speech is presented. It is based on the Standard Model of Mind, integrated with modules for self-talking. Briefly, the working memory of the proposed architecture includes the phonological loop as a component which manages the exchanging information between the phonological store and the articulatory control system. The inner dialogue is modeled as a loop where the phonological store hears the inner voice produced by the hidden articulator process. A central executive module drives the whole system, and contributes to the generation of conscious thoughts by retrieving information from long-term memory. The surface form of thoughts thus emerges by …

Cognitive scienceSettore ING-INF/05 - Sistemi Di Elaborazione Delle InformazioniComputer scienceWorking memoryCognitive Neurosciencemedia_common.quotation_subjectInner speechExperimental and Cognitive PsychologyContext (language use)Cognition02 engineering and technologyCognitive architectureCognitive architecture03 medical and health sciences0302 clinical medicineArtificial IntelligencePerception0202 electrical engineering electronic engineering information engineering020201 artificial intelligence & image processingBaddeley's model of working memoryEvent calculus030217 neurology & neurosurgerySoftwareHumanoid robotmedia_common
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